Magic mushrooms may give users trippy experiences by creating a hyperconnected brain. The active ingredient in the psychedelic drug, psilocybin, seems to completely disrupt the normal communication networks in the brain, by connecting “brain regions that don’t normally talk together,” said study co-author Paul Expert, a physicist at King’s College London. The research, which was published today (Oct. 28) in the Journal of the Royal Society Interface, is part of a larger effort to understand how psychedelic drugs work, in the hopes that they could one day be used by psychiatrists — in carefully controlled settings — to treat conditions such as depression, Expert said. [Trippy Tales: The History of 8 Hallucinogens]
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